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KTVO is the ABC-affiliated television station for the Heartland (United States) area of Northeastern Missouri and Southeastern Iowa.

Licensed to Kirksville, Missouri, it broadcasts a high-definition digital signal on UHF channel 33 from a transmitter northwest of Downing, Missouri along US 136.

The station can also be seen in Iowa on Mediacom channel 5 (HD on digital channel 803) and in Missouri on Cable One channel 6 (HD on digital channel 455).

Owned by Sinclair Broadcast Group, KTVO's main broadcast facility is located on US 63 two miles north of Kirksville.

The station has an additional news studio and operations that are maintained at 111 South Market Street in downtown Ottumwa, Iowa.

KTVO.com provides news, sports and weather coverage and serves the area around Kirksville, Missouri and Ottumwa.

Counties served in Missouri include: Adair, Sullivan, Macon, Putnam and Schuyler.

Iowa counties served include: Wapello, Jefferson, Davis and Van Buren.