The Daytona Beach Campus, Daytona States largest campus, is located in a tourist city that attracts more than 10 million visitors each year, including snowbirds, students on spring break, families on vacation, NASCAR race fans and 500,000 bikers who come on motorcycles each spring and fall for Daytonas famous Bike Weeks.

The campus houses the college's primary administrative offices and instructional space. Special features include the Mori Hosseini College of Hospitality and Culinary Management, home to the student-run Cafe 101 and the Southeast Museum of Photography; a full-service Learning Resource Center that also houses the library and DSC Writing Center; two locations for the Academic Support Center; and a Performing Arts Center, which is home to some of the area's finest performing arts productions. Also located on this campus is the Lemerand Center, an outstanding athletic multiplex with a fitness center, pool, gymnasium, and classrooms; Daytona States WDSC TV-15 broadcasting station; and a joint-use facility shared with the University of Central Florida.

Classroom and laboratory space serve a range of academic offerings from baccalaureate programs to associate of arts, associate of science and certificate programs; adult high school, general education development and adult basic education; and customized training for business and industry. More than 24,000 students on average attend the Daytona Beach Campus each year.